Alcohols and weakly acidic phenols which do not react with diazomethane can be methylated in the presence of acid catalysts 2.3 , but certain hindered alcohols 2,3 and phenols 3 react with difficulty or not at all. We describe here the use of sodium hydride / methyl iodide in tetrahydrofuran (THF) a
✦ LIBER ✦
Rearrangements and unusual reductions with sodium hydride and methyl iodide
✍ Scribed by Helmut Duddeck; H. -Thomas Feuerhelm; Günter Snatzke
- Book ID
- 104237592
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- French
- Weight
- 119 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
In the course of our 13 C NMR investigations of adamantane derivatives we wanted to prepare the 4-methoxyadamantanones 2 and Al. To that end we refluxed the cor-
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