Rearrangement of 12q14-15 in pulmonary chondroid hamartoma
β Scribed by Paola Dal Cin; Patrick Kools; Inge De Jonge; Phillippe Moerman; Wim Van De Ven; Herman Van Den Berghe
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 227 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1045-2257
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β¦ Synopsis
Cytogenetic analysis of a pulmonary chondroid hamartoma showed an in! together with previously reported data is an indication that the 12q pathogenesis of this tumor type.
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Banding cytogenetics and fluorescence in situ hybridization analysis of a pulmonary chondroid hamartoma (PCH) showed the presence of a t ( 6 I O)(p2 I ;q22). A cytogenetically identical translocation has previously been found in another case of PCH, suggesting that it could represent a variant form
Pulmonary chondroid hamartomas (PCHs) are benign mesenchymal tumors that often are characterized by specific chromosomal aberrations. Herein we report our cytogenetic and molecular cytogenetic (FISH) studies on 191 PCHs, including 48 previously published cases. In this series, 134/191 PCHs (70.2%) s
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