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An identical HMGIC-LPP fusion transcript is consistently expressed in pulmonary chondroid hamartomas with t(3;12)(q27–28;q14–15)

✍ Scribed by Piere Rogalla; Inga Lemke; Bernd Kazmierczak; Jörn Bullerdiek

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
115 KB
Volume
29
Category
Article
ISSN
1045-2257

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✍ Piere Rogalla; Bernd Kazmierczak; Kerstin Meyer-Bolte; Kim Hue Tran; Jörn Buller 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 215 KB

The HMGIC gene, located in chromosome band 12q15, is rearranged in many different benign human tumors, often resulting in its fusion to ectopic sequences from other genes. The t(3;12)(q27;q14-q15) fuses HMGIC with the LPP gene and has so far been described exclusively in lipomas. Thus, it can be hyp