The Epstein-Barr virus (EBV) has been studied for over 25 years as a probable cause of certain human cancers, including nasopharyngeal carcinoma (NPC). This is a low-incidence head and neck cancer in Western countries (including the USA), but is the third-leading cancer in males in Southeast Asia. E
Rearranged Epstein-Barr Virus Genomes and Clonal Origin in Nasopharyngeal Carcinoma
β Scribed by Shimakage, Misuzu ;Chatani, Masashi ;Ikegami, Nobuko ;Hirai, Kanji
- Book ID
- 108578831
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1989
- Tongue
- English
- Weight
- 285 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0910-5050
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## Abstract ## Background Little has been known about whether EpsteinβBarr virus (EBV) could persist in nasopharyngeal carcinoma (NPC) cells by chromosomal integration, and no NPC cell line harboring integrated EBV has been reported. In this study, we explored this issue through isolating EBVβinfe
## Abstract In order to explore whether undifferentiated nasopharyngeal carcinoma (NPC) shows a regular association with EpsteinβBarr virus (EBV), regardless of the geographical and ethnic origin of the patient, a correlated histopathological and nucleic acid hybridization study was performed on bi