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Epstein-Barr virus and nasopharyngeal carcinoma

✍ Scribed by Dr. Gary R. Pearson

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
411 KB
Volume
53
Category
Article
ISSN
0730-2312

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✦ Synopsis

The Epstein-Barr virus (EBV) has been studied for over 25 years as a probable cause of certain human cancers, including nasopharyngeal carcinoma (NPC). This is a low-incidence head and neck cancer in Western countries (including the USA), but is the third-leading cancer in males in Southeast Asia. Evidence supporting an etiologic relation between this virus and NPC includes the fact that there is a 100% infection rate in patients with this cancer and that EBV DNA and antigens have been demonstrated in all biopsies examined to date. The determination that EBV is at least a major co-factor in the etiology of NPC has led to the development of new diagnostic and prognostic tests for this disease using anti-viral markers. Of particular importance to the diagnosis of NPC were

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