Reappraisal of the Importance of Amino Acids 70 Substitutions in the Core Region of Hepatitis C Virus in Serum Lipid Markers of Patients With Chronic Hepatitis C Genotype 1b and High Load Treated With Interferon and Ribavirin
β Scribed by Ishii, Koji ;Kogame, Michio ;Kanayama, Kaori ;Shinohara, Mie ;Higami, Katsuya ;Sumino, Yasukiyo
- Book ID
- 122168490
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 94 KB
- Volume
- 140
- Category
- Article
- ISSN
- 0016-5085
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biochemical and histological improvement. 3,4 Several factors Hepatitis C virus (HCV) genotype 1b and high precan predict a poor response to interferon therapy, e.g., high treatment virus load are predictive factors of poor repretreatment virus load, genotype 1b, advanced histological sponse to inte
## Abstract It has been reported that genetic polymorphisms near the __IL28B__ gene or amino acid substitutions in hepatitis C virus (HCV) core protein are associated with the clinical outcome of peginterferon (PEGβIFN) and ribavirin combination therapy. The impact of these factors on the pure sens
## Abstract Substitution of amino acid (aa) 70 and 91 in the core region of hepatitis C virus (HCV) genotype 1b can predict the response to pegylated interferon (PEGβIFN)/ribavirin combination therapy, but its impact on triple therapy of telaprevir/PEGβIFN/ribavirin is not clear. The aims of this s
## Abstract Previous studies identified amino acid (aa) substitutions of the hepatitis C virus core region of genotype 1b (HCVβ1b core region) and elevated serum alphaβfetoprotein (AFP) levels as predictors of poor virologic response to pegylated interferon (PEGβIFN) plus ribavirin (RBV), and also