𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Reading within the lines: naturally processed peptides displayed by MHC class I molecules

✍ Scribed by Nilabh Shastri; Thomas Serwold; Pedro Paz

Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
742 KB
Volume
10
Category
Article
ISSN
0952-7915

No coin nor oath required. For personal study only.

✦ Synopsis

A typical mammalian cell contains tens of thousands of different gene products. Snippets of this genetic information are displayed on the cell surface by MHC class I molecules as short peptides for immune surveillance by CD8 + T lymphocytes. Genetic and biochemical analysis of these peptides is revealing novel sources and mechanisms by which these peptide/MHC class I complexes arise.

πŸ“œ SIMILAR VOLUMES

Multiple class I motifs revealed by sequ
Multiple class I motifs revealed by sequencing naturally processed peptides eluted from rat T cell MHC molecules
✍ G.G. Burrows; K. Ariail; B. Celnik; J.E. Gambee; H. Offner; A.A. Vandenbark πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 153 KB

Class I major histocompatibility complex (MHC) molecules interact with a diverse array of self and foreign peptides. Displayed on the cell surface, the class I/peptide complex provides an extracellular indication of the intracellular milieu. We have characterized the Lewis rat Vb8.21 T cell hybridom

The set of naturally processed peptides
The set of naturally processed peptides displayed by DR molecules is tuned by polymorphism of residue 86
✍ StΓ©phane Demotz; Catherine Barbey; Giampietro Corradin; Antonio Amoroso; Antonio πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 827 KB

## Abstract The response to tetanus toxoid (TT) was studied in immune donors that carry two alleles of DR5 that differ only at DRΞ² residue 86: DRB1\*1101 (G86, abbreviated 1101) and DRB1\*1104 (V86, abbreviated 1104). A large number of TT‐specific T cell clones was isolated and the epitopes recogni

Variation in H-2Kk peptide motif reveale
Variation in H-2Kk peptide motif revealed by sequencing naturally processed peptides from T-cell hybridoma class I molecules
✍ G.G. Burrows; K. Ariail; B. Celnik; J.E. Gambee; B.F. Bebo Jr.; H. Offner; A.A. πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 800 KB

Class I major histocompatibility complex (MHC) molecules interact with a diverse array of self and foreign peptides, displaying them on the cell surface and providing an extracellular indication of intracel-M a r invasion. The most clearly defined role for these class Upeptide complexes is to cause