Exogenous peptides enter the endoplasmic
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Jonathan M. Levitt; Dewey D. Howell; John R. Rodgers; Robert R. Rich
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Article
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2001
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John Wiley and Sons
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English
⚖ 169 KB
MHC class I molecules assemble within the endoplasmic reticulum (ER) in complexes that include g 2-microglobulin ( g 2 m), the transporter associated with antigen processing (TAP) and several additional chaperones. Release of class I complexes from the ER is thought to require the binding of an appr