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Reactivity of thienopyrroles. Synthesis of isomeric nitro and bromothienopyrroles

✍ Scribed by J. Eras; C. Gálvez; F. Garct́a


Book ID
112127365
Publisher
Journal of Heterocyclic Chemistry
Year
1984
Tongue
English
Weight
208 KB
Volume
21
Category
Article
ISSN
0022-152X

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Silyl nitronates are readily generated from carbohydrates containing a nitromethyl group; these nitronates participate in F--catalyzed nitroaldol reactions with aldehydes provided that the nucleophilic carbon atom is sufficiently remote from the cyclic carbohydrate moiety.