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Reactivity and Geometry in Allylic Systems. V. Oxygenation of Cholest-5-en-3-one 1

✍ Scribed by Nickon, A.; Mendelson, W. L.


Book ID
127335580
Publisher
American Chemical Society
Year
1965
Tongue
English
Weight
444 KB
Volume
30
Category
Article
ISSN
0022-3263

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(25R)-5 alpha-Cholest-8(14)-ene-3 beta,15 beta,26-triol (III) was prepared by reduction of (25R)-3 beta,26-diacetoxy-5 alpha-cholest-8(14)-en-15-one with sodium borohydride followed by treatment of the crude product with lithium aluminium hydride. The trihydroxysterol III, a potential metabolite of