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Reactive Oxygen Species Participate in Peroxynitrite-Induced Apoptosis in HL-60 Cells

✍ Scribed by King-Teh Lin; Ji-Yan Xue; Frank F. Sun; Patrick Y-K Wong


Book ID
115579594
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
161 KB
Volume
230
Category
Article
ISSN
0006-291X

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Peroxyacetyl nitrate (PAN), an ubiquitous air pollutant, induced apoptosis in human leukemia HL-60, human chronic myelogenous leukemia K-562, and mouse monocyte-macrophage RAW 264.7 cell lines. In the HL 60 cells, characteristic apoptosis morphology could be observed 4 h after the cells were treated