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Reactive Oxygen Species Mediate Alpha-adrenergic Receptor-stimulated Hypertrophy in Adult Rat Ventricular Myocytes

✍ Scribed by Jay K Amin; Lei Xiao; David R Pimental; Patrick J Pagano; Krishna Singh; Douglas B Sawyer; Wilson S Colucci

Book ID
115633153
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
215 KB
Volume
33
Category
Article
ISSN
0022-2828

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## Abstract We have shown that the stimulation of β‐adrenergic receptors (β‐AR) increases apoptosis in adult rat ventricular myocytes (ARVMs). Integrins, a family of αβ‐heterodimeric cell surface receptors, are postulated to play a role in ventricular remodeling. Here, we show that norepinephrine (