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Reactive oxygen species have a causal role in multiple forms of insulin resistance

✍ Scribed by Houstis, Nicholas; Rosen, Evan D.; Lander, Eric S.

Book ID: 109895736
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 406 KB
Volume: 440
Category: Article
ISSN: 0028-0836
DOI: 10.1038/nature04634

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## Abstract Increased oxidative stress plays an important role in vascular dysfunction and atherogenesis. Both systemic factors, such as hypercholesterolemia and hyperglycemia, and local factors, such as activation of macrophages and T cells, may contribute to oxidative stress. Oxidation of lipids