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Reactive Oxygen Species as Mediators of Cellular Senescence

✍ Scribed by Renata Colavitti; Toren Finkel

Book ID
111741651
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
187 KB
Volume
57
Category
Article
ISSN
1521-6543

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Reactive oxygen species (ROS) are known to be involved in different pro- and anticarcinogenic mechanisms. However, their influence on the maintenance of the transformed phenotype has not been studied so far. Here we show that the anchorage-independent growth of transformed murine fibroblasts is inhi