✦ LIBER ✦

Reactive hyperemia monitored on rat muscle using perfluorocarbons and 19F NMR

✍ Scribed by Bertrand Authier

Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 231 KB
Volume: 8
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910080109

No coin nor oath required. For personal study only.

✦ Synopsis

Perfluorinated blood substitutes can be detected by I9F NMR in vivo in small concentrations. Reactive hyperemia was induced in rat leg by the transient application of a tourniquet, causing a 50% increase in I9F NMR signal. These results show that this method can be used to monitor the kinetics of tissue perfusion. o 1988 Academic press, Inc.

Perfluorinated blood substitutes are currently investigated in the field of N M R as contrast agents for M R imaging and spectroscopy (I). When injected, they stay intra-0740-3194/88 $3.00 80

(1,2).

📜 SIMILAR VOLUMES

Studies on the metabolism of fluorinated

Studies on the metabolism of fluorinated xenobiotics in the rat using 19F-NMR and 1H-NMR spectroscopy

✍ F.Y.K. Ghauri; C.A. Blackledge; I.D. Wilson; J.K. Nicholson 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 289 KB

Dynamic Monitoring of Total-Body Absorpt

Dynamic Monitoring of Total-Body Absorption by 19F NMR Spectroscopy: One Hour Ventilation of HFA-134a in Male and Female Rats

✍ John R. Finch; Eric J. Dadey; Stanford L. Smith; Lester I. Harrison; George A. D 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 441 KB

## Abstract Six male and six female Sprague‐Dawley rats were ventilated head‐only for 1 h on a 15% atmosphere of 1, 1, 1, 2‐tetrafluoroethane (HFA‐134a) in air in a magnetic resonance imaging spectrometer. Results from these dynamic ^19^F NMR studies suggest that a steady‐state __in vivo__ concentr