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Reactivation of sarin-inhibited pig brain acetylcholinesterase using oxime antidotes

✍ Scribed by Kamil Kuca; Daniel Jun

Book ID
105718901
Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
158 KB
Volume
2
Category
Article
ISSN
1556-9039

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Comparison of in vitro potency of oximes
Comparison of in vitro potency of oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited acetylcholinesterase in various parts of pig brain
✍ Kamil Kuca; Jiri Cabal; Jiri Kassa; Daniel Jun; Martina HrabinovΓ‘ πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 150 KB

The potency of currently used oximes to reactivate sarin-inhibited acetylcholinesterase (AChE) in various parts of pig brain and whole pig brain was evaluated using in vitro methods. Significant differences in reactivation potency among all tested oximes were observed. At concentrations (10 - ----4