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Potency of new structurally different oximes to reactivate cyclosarin inhibited-human brain acetylcholinesterases

✍ Scribed by Kamil Kuca; Jiri Cabal; Daniel Jun; Jiri Bajgar; Jiri Kassa; Josef Fusek

Book ID
108287313
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
61 KB
Volume
233
Category
Article
ISSN
0300-483X

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πŸ“œ SIMILAR VOLUMES

New methods in synthesis of acetylcholin
New methods in synthesis of acetylcholinesterase reactivators and evaluation of their potency to reactivate cyclosarin-inhibited AChE
✍ K. MusΓ­lek; L. Lipka; V. RačÑkovΓ‘; K. Kuča; D. Jun; V. Dohnal; M. DoleΕΎal πŸ“‚ Article πŸ“… 2006 πŸ› Versita 🌐 English βš– 194 KB

## Abstract Nine potential AChE reactivators were synthesized using modification of currently known synthetic pathways. Their potency to reactivate AChE inhibited by cyclosarin nerve agent was tested in vitro. According to the previous results, 1,4-bis(2-hydroxyiminomethylpyridinium)butane dibromid