Reactions of β-fluorovinamidinium salt with bifunctional hetero nucleophiles. A new synthetic route to fluorinated heterocycles
✍ Scribed by Xifeng Shi; Takashi Ishihara; Hiroki Yamanaka; John T. Gupton
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 207 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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## Abstract The [4 + 2] cycloadditions of 2‐oxobut‐3‐enenitrile (1a), 2‐oxopent‐3‐enenitrile (1b), and ethyl 4‐cyano‐4‐oxobut‐2‐enoate (1c) with 1,3‐dimethyluracil (2), 1,3, 6‐trimethyluracil (9), or 1,3,5‐trimethyluracil (16) were investigated. The reactions of 1a with 2 or with 9 lead to bicyclic