𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cyclizations of 1,2,4-triazinium salts with bifunctional nucleophiles - a new route to condensed 1,2,4-triazines

✍ Scribed by S.G. Alexeev; V.N. Charushin; O.N. Chupakhin; G.G. Alexandrov

Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
226 KB
Volume
29
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

The reaction of 1,2,4-triazinium salts with amides of acetoacetic acid yielding ,7,7a-hexahydro-6H-pyrrolo[3,2-e]-1,2,4-triazin-6-ones exemplifies the first direct to the 1,2,4-triazine ring based on the diaddition of bifunctional nucleophiles at C-5 and C-6.

πŸ“œ SIMILAR VOLUMES

A New Route to Pyrazolo[3,4-e]-1,2,4-tri
A New Route to Pyrazolo[3,4-e]-1,2,4-triazines
✍ Sadek, Kamal Usef ;Abouhadid, Khalid ;Elghandour, Ahmed Hafez Hussein πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 194 KB πŸ‘ 1 views
A new route to functionalized 3-aminopyr
A new route to functionalized 3-aminopyridazines by ANRORC type ring transformation of 1,2,4-triazines with carbon nucleophiles
✍ Andrzej Rykowski; Ewa Wolinska; Henk C. Van Der Plas πŸ“‚ Article πŸ“… 2000 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 314 KB

## Abstract The reaction of 3‐chloro‐6‐phenyl‐1,2,4‐triazine **1a** with carbon nucleophiles **2aο£Ώd** bearing a cyano substituent at a carbanionic center has been studied. In all reactions the formation of the corresponding 3‐aminopyridazines **3aο£Ώd** takes place via ANRORC mechanism involving addi