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Reactions of the aminoacyl-tRNA synthetase-aminoacyl adenylate complex and amino acid derivatives A new approach to peptide synthesis

โœ Scribed by Hiroshi Nakajima; Senji Kitabatake; Ryoichi Tsurutani; Isao Tomioka; Keiichi Yamamoto; Kazutomo Imahori


Book ID
113264680
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
266 KB
Volume
790
Category
Article
ISSN
0167-4838

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Leucyl/phenylalanyl(L/F)-tRNA-protein tr
โœ Masumi Taki; Masahiko Sisido ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 236 KB

## Abstract We report here a new strategy for derivatizing peptides and proteins at the Nโ€terminus. To achieve this, a nonnatural amino acid was charged onto a tRNA and then enzymatically transferred to a lysine (Lys) unit at the Nโ€terminus of a peptide or a protein by using L/Fโ€tRNAโ€protein transf