## Abstract For Abstract see ChemInform Abstract in Full Text.
Metal-catalysed reaction of β-dicarbonyls with ethyl cyanoformate: a new approach to the synthesis of unsaturated amino acid derivatives
✍ Scribed by A.C. Veronese; V. Gandolfi; B. Longato; B. Corain; M. Basato
- Publisher
- Elsevier Science
- Year
- 1989
- Weight
- 454 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0304-5102
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Several synthetic /J,f-unsaturated &amino acids have recently been developed as specific irreversible inhibitors of pyridoxal l,hosl,hate dependent enzymes. 1 A few naturally occurring P,d-unsaturated amino acids are known to function as specific enzyme inhibitors 2. including rhizobitoxine inhibiti
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Transition Metal/Base-Catalyzed Aldol Reactions of Isocyanoacetic Acid Derivatives with Prochiral Ketones, a Straightforward Approach to Stereochemically Defined β,β-Disubstituted-β-hydroxy-. alpha.amino Acids. Scope and Limitations. -Methyl isocyanoacetate (II) undergoes aldol type reactions with