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Reactions of the amide side-chains of glutamine and asparagine in vivo

✍ Scribed by Wold, Finn


Book ID
121946007
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
303 KB
Volume
10
Category
Article
ISSN
0968-0004

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S)-b 2 -Homoamino acids with the side chains of Asp, Glu, Asn, and Gln have been prepared and suitably protected (N-Fmoc, CO 2 t Bu, CONHTrt) for solid-phase peptide syntheses. The key steps of the syntheses are: N-acylation of 5,5-diphenyl-4-isopropyl-1,3-oxazolidin-2-one (DIOZ) with succinic and g