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Reactions of silyl nitronates with dimethylformamide dimethyl acetal as a new general procedure for the synthesis of 2-nitroenamines

✍ Scribed by Shved, Alexander S.; Tabolin, Andrey A.; Khomutova, Yulia A.; Ioffe, Sema L.


Book ID
126734661
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
685 KB
Volume
55
Category
Article
ISSN
0040-4039

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A new method for the synthesis of g-butanolides is described. The titanium tetrachloride promoted reaction of silyl ketene acetals with epoxides, followed by acidic work-up, affords the corresponding butyrolactones in 44-83% yield.