Reactions of dihydronicotinamides II. The acid-catalyzed dimerization of 1-benzyl-1,4-dihydronicotinamide
✍ Scribed by James J. Steffens; John P. Cross; David M. Chipman
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- French
- Weight
- 219 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
02139 (R8ceived in IJR 12 Cctober 1972; acoepted for publication 26 Octobar 1972) le would like to report the dimerization of I-benzyl-1,4-dihydronicotinamide in acidic aqueous suspension to form the polycyclic cage molecule 1 in high yield. Although
📜 SIMILAR VOLUMES
HEXACHLOROACETONE is very readily reduced to hexachloroisopropanol by I-benzyl-l,f+-dihydronicotinamide. The reduction goes violently at room and is accompanied went vigorously. temperature in the absence of solvent, is exothermic, by formation of a black tar. Even at 0' the reaction cc13cocc13 + HC
din&&den were hound Xo be teduced bmootkey to Xhc c~~netkio.R~ by BNAff a ca&Cy.tic amount 06 3-mtihy&?umi#auin undeh mad conditions. The redox reaction between thiol and disulfide is very important in living bodies. 2)(eq.l) This reaction is promoted by emzymes, such as lipoamide dehydrogenase, glu
sumtnmy : Redution 06 dicvry1 dAuR,jideA with I-benzyt-l,4-dihydtronicofivmmide (ENAH] ptoceeded &tough a had-&at chain heation, wkiee di.a.tkyL dhu&du wem dound to be inat to BNAH. Thiols, such as glutathione, and redox enzymes whose active site possesses two cysteine residues in proximity, reduce
## Abstract The photoinduced reaction of a mixture of (Z)‐α‐cyano‐β‐bromomethylcinnamide (1) and (__E__)‐α‐cyano‐β‐bromomethylcinnamide (2) with 1‐benzyl‐1, 4‐dihydronicotinamide produces a mixture of the (__E__)‐ and (__Z__)‐ isomers of α‐cyano‐β‐methylcinnamide (3 and 4). Using spin‐trapping tech