## Abstract Nitrile oxides 2a, b and nitrile imines 2c–e are added to the C C bond of 4‐arylidene‐2‐phenyl‐5(4__H__)‐thiazolones 1 to afford spiro‐isoxazolines 3a–d and spiro‐pyrazolines 3e–j, respectively. The cycloaddition reactions are regioselective and only one of the two possible regioisome
Reactions of cyclopropenes with nitrile oxides and nitrile imines
✍ Scribed by J.P. Visser; P. Smael
- Publisher
- Elsevier Science
- Year
- 1973
- Tongue
- French
- Weight
- 114 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0040-4039
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## Abstract The readily available alkyl dicyanoacetates 1 reacted with the 1,3‐dipolar reagents arenecarbonitrile oxides 2′ and arenecarbonitrile imines 5′ to afford 1,2,4‐oxadiazol and 1,2,4‐triazol derivatives. The arenecarbonitrile oxides 2′ with electron‐donating groups on the arene ring gave p
The tormation of 1,2,4-oxadiazoles is frequently observed as a side reaction in cycle additions with nitrile oxides generated in situ and follows from a fragmentation induced by Et3N. This latter is oxidized to N,N-diethylvinylamine, which is trapped as a cycloadduct. 4litrile oxides are usually gen
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