Reactions of carbethoxycarbene with enaminones. Formation of unexpected pyrroles
โ Scribed by Rodinei Augusti; Marcos N. Eberlin; Concetta Kascheres
- Book ID
- 112131335
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1995
- Tongue
- English
- Weight
- 249 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The reaction of thioamides with DMAD gave the pyrrole derivatives in good yield and the thiophene derivatives as a byproduct. These were formed by 1,3-dipolar cycloaddition of themodynamicaly stable azomethine ylide or less stable thiocarbonyl ylide with DMAD, followed by elimination of thioaldehyde
Formation of Highly Substituted Pyrrole Derivatives: An Unexpected Domino Reaction. -If the reaction is performed with 13 C methyl labeled amine (Ia), the carbon atom is found in the benzyl-substituted 3-position of pyrrole (IIIa). On the basis of this result a mechanism is proposed for the reaction