Reactions of azirines with sulfur nucleophiles. 4. Treatment of 2H-azirine with mercaptosubstituted acids. reactions of aziridinyl alkyl sulfides with carboxylic acids and acyl chloride derivatives
✍ Scribed by R. S. Él'kinson; A. V. Eremeev
- Book ID
- 112359571
- Publisher
- Springer US
- Year
- 1986
- Tongue
- English
- Weight
- 447 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0009-3122
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📜 SIMILAR VOLUMES
Recently, we tried to establish the proposed reaction mechanism by proceeding the reaction at lower temperature and with differently substituted 3-amino-7'2-azirines 1 in order to isolate the postulated intermediate C. ## 4, Determined by potentiomemc titration.
## Abstract Acid chlorides and anhydrides react with 2‐amino‐4‐alkyloxazoles in the presence of aluminum chloride to produce 5‐acyl substituted 2‐amino‐4‐alkyloxazoles in modest yields. However, in the absence of the Lewis acid reaction occurs at the amino group to give the corresponding amides. Th