Reaction of 3-Amino-2H-azirines with 2-Amino-4,6-dinitrophenol (Picramic Acid): Synthesis of Quinazoline- and 1,3-Benzoxazole Derivatives
✍ Scribed by José M. Villalgordo; Beverly R. Vincent; Heinz Heimgartner
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- German
- Weight
- 797 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Recently, we tried to establish the proposed reaction mechanism by proceeding the reaction at lower temperature and with differently substituted 3-amino-7'2-azirines 1 in order to isolate the postulated intermediate C.
4,
Determined by potentiomemc titration.
📜 SIMILAR VOLUMES
## Abstract The reaction of 3‐__N__‐(2‐mercapto‐4‐oxo‐4__H__‐quinazolin‐3‐yl)acetamide (**1**) with hydrazine hydrate yielded 3‐amino‐2‐methyl‐3__H__‐[1,2,4]triazolo[5,1‐__b__]quinazolin‐9‐one (**2**). The reaction of **2** with __o__‐chlorobenzaldehyde and 2‐hydroxy‐naphthaldehyde gave the corresp
## Abstract For Abstract see ChemInform Abstract in Full Text.
A new synthesis of a series of 3-amino-1H-quinazoline-2,4-diones is described. The 1H-quinazoline-2,4dione 10 was made starting with fluorobenzoic acid in three high yielding steps. The key step of this synthesis involved the generation of the dianion of urea 7 and the subsequent intramolecular nucl