Reaction of β-fluorovinamidinium salt with Grignard reagents. Facile and efficient route to (Z)-α-fluoro-α,β-unsaturated aldehydes
✍ Scribed by Hiroki Yamanaka; Yasumasa Odani; Takashi Ishihara; John T Gupton
- Book ID
- 108386997
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 223 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
2,3,3-Trifluoro-l-pmpenyl p-chlorobenzenesulfonate (1), readily available from 2,2,3,3tetrafluoropmpanol, reacted smoothly with various Grignard reagents at 50 °(3 to afford the corresponding (Z)-a, fl-difluoroallyl alcohols 2 in moderate to excellent yields. These alcohols were smoothly hydrolyzed
Ultrasound Accelerated Coupling Reaction of Grignard Reagents with 1,3-Dioxolanes of α,β-Unsaturated Aldehydes. -Allylic ethers are obtained in high yields by coupling of 1,3-dioxolanes of α,β-unsaturated aldehydes with Grignard reagents under mild conditions. The reaction, which is enhanced by ult