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Reaction of pyrimidin-2(1H)-ones and -thiones with organometallic compounds. Regioselective preparation of dihydropyrimidin-2(1H)-ones and -thiones

✍ Scribed by Kashima, Choji; Katoh, Akira; Yokota, Yuko; Omote, Yoshimori


Book ID
115494124
Publisher
Royal Society of Chemistry
Year
1981
Weight
464 KB
Volume
0
Category
Article
ISSN
1472-7781

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Three Component Reaction: An Efficient S
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## Abstract Fluoroboric acid supported on silica gel (HBF~4~‐SiO~2~) catalyzes efficiently the three component condensation of an aldehyde, a 1,3‐dicarbonyl compound and urea or thiourea to afford the corresponding 3,4‐dihydropyrimidin‐ 2(1__H__)‐ones and thiones in high yields. The ambient conditi