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Iron(III) tosylate catalyzed synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones via the Biginelli reaction

โœ Scribed by Starcevich, Jacob T.; Laughlin, Thomas J.; Mohan, Ram S.


Book ID
118255809
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
363 KB
Volume
54
Category
Article
ISSN
0040-4039

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A one-pot Biginelli synthesis of 3,4-dih
โœ Abdelmadjid Debache; Mouna Amimour; Ali Belfaitah; Salah Rhouati; Bertrand Carbo ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 163 KB

We report herein the use of triphenylphosphine (TPP) as a new catalyst for the one-pot Biginelli reaction coupling of b-ketoesters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones/thiones.