Reaction of pyridazine n-oxides with organometallic compounds
โ Scribed by Hiroshi Igeta; Takashi Tsuchiya; Toshiko Nakai
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- French
- Weight
- 223 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
Although reactions of organometallic compounds with aromatic amines 2) and their N-oxides 3) have been investigated, similar reactions with pyridazines have 4,5) only recently been examined
, and there are no reports of such reactions with pyridazine N-oxides.
We now report the formation of three kinds of hydrocarbons; monophenyl-sub-
๐ SIMILAR VOLUMES
The reaction of diphenyl(methoxymethyl)phosphine oxide 1 with organometallic reagents was found to lead to substitution of the methoxymethyl group. The P-phenyl substituent showed a lower propensity to undergo a displacement.
We have already reported 2,3 that the reaction of 1-methylpyridazinium
In a previous paper2), we reported that irradiation of pyridazine N-oxides in benzene or toluene as solvent, resulted in the formation of the corresponding phenols, derived from the solvent, in 30-40s yield based on the N-oxides consumed.