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Reaction of phenyl isocyanate with N-methyl-2-pyrrolidinone

โœ Scribed by Richter, Reinhard; Ulrich, Henri


Book ID
126072142
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
563 KB
Volume
38
Category
Article
ISSN
0022-3263

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Synthesis of [4-3H]-2-pyrrolidinone, [4-
โœ David A. Wells; James E. Chaney; George A. Digenis ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 544 KB

An efficient synthesis of 2-pyrrolidinone and N-methyl-2-pyrrolidinone was developed in which the compounds can be labeled with tritium at either the 3-and 4-positions or the 4-position of the lactam ring. Cyclization of [2 3-3Hl-yarninobutyric acid (GABA) yielded [ 3, $-$I -2pyrrolidinone and cycli