Reaction of .omega.-chloro ketones with methylenetriphenylphosphorane
โ Scribed by Pasto, Daniel J.; Garves, Klaus; Sevenair, John P.
- Book ID
- 127080718
- Publisher
- American Chemical Society
- Year
- 1968
- Tongue
- English
- Weight
- 440 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
One of the most extensively utilized reactions involving phosphorus ylides is the Wittig reaction with carbouyl compounds to produce olefins and a phosphine oxide. Numerous mechanistic aud synthetic investigations have appeared ou the Wittig reaction and the gross mechanistic features are reasouably
Experimental details are provided to support a previous report that c+methylenetriphenylphosphorane ( &, ) may be activated for reaction with unreactive substrates such as epoxides and hindered ketones by o-metallation to 2\_. It has recently been discovered in this laboratory' that methylenetriphe