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Reaction of lithium N-isopropylcyclohexylamide with esters. Method for the formation and alkylation of ester enolates

โœ Scribed by Rathke, Michael W.; Lindert, Andreas


Book ID
111879560
Publisher
American Chemical Society
Year
1971
Tongue
English
Weight
402 KB
Volume
93
Category
Article
ISSN
0002-7863

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The reaction of lithium ester enolates w
โœ Michael W. Rathke; Jeffrey Deitch ๐Ÿ“‚ Article ๐Ÿ“… 1971 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 158 KB

Lithium ester enolates, prepared by the reaction of lithium N-isopropylcyclohexylamide (LIICA) with esters at -78' (eq. 1); react with acid chlorides at this same low temperature to provide satisfactory yields of the corresponding S-keto esters (eq. II). This procedure represents an exceedingly vers