Several synthons of b-carboxy carbanions (2) have been added to aldehydes and/or ketones the products ultimately converted into y-butyrolactones Q).l However, this methodology normally requires the use of system. We wish to report a B-lithiopropionate (2) to an adduct. complex reagents and/or severa
✦ LIBER ✦
Reaction of dilithiated 1,2-diesters with β-bromoethyloxirane. Synthesis of annelated γ-lactones
✍ Scribed by Peter J Garratt; John R Porter
- Book ID
- 104227383
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 118 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0040-4039
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In the crystal, the molecule has C, symmetry (Fig. ); its conformation essentially corresponds to that which, according to MNDO calculations and NMR data, is the more stable of the two conformations in The benzene ring has an unsymmetric boat conformation, whose most striking characteristic is the m