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Reaction of 5,5-diphenyl-2-thiohydantoin with ethyl chloroacetate: Synthesis and crystal and molecular structure of 2,3,5,6-tetrahydroimidazo-[2,1-b]-thiazol-3,6-dione

✍ Scribed by Katarzyna Kieć-Kononowicz; Janina Karolak-Wojciechowska; Witold Kwiatkowski


Publisher
Springer
Year
1988
Tongue
English
Weight
534 KB
Volume
18
Category
Article
ISSN
1572-8854

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Synthesis and Crystal Structure of 3,3,6
✍ Nasser Mawad; Fatemeh Ghorbani-Salman Pour; Anthony Linden; Heinz Heimgartner 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 German ⚖ 360 KB

The synthesis of 3,3-dimethylmorpholine-2,5-diones 4a was achieved conveniently via the direct amide cyclization of the linear precursors of type 3, which were prepared by coupling of 2,2-dimethyl-2H-azirin-3-amines 2 with 2-hydroxyalkanoic acids 1. Thionation of 4a with Lawessons reagent yielded th