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Reaction of 5-diazouracils with pyridines

โœ Scribed by Keen, Brian T.; Paudler, William W.

Book ID
125969179
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
457 KB
Volume
40
Category
Article
ISSN
0022-3263

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In the presence of rhodium acetate 5diazouracil reacts with varied secondary amines, azoles and thiols to give 5-substituted-uracils efficiently. 5Diazouracil (1) is a significant bactericidela and carcinostatlb. As yet, however, reactions of 1 with nucleophiles am not been well defmed. k-f Water a