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5-Diazouracils in Azo Coupling Reactions.

✍ Scribed by E. B. Tsupak; M. A. Shevchenko; Yu. N. Tkachenko; D. A. Nazarov


Book ID
101937229
Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
33
Category
Article
ISSN
0931-7597

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In the presence of rhodium acetate 5diazouracil reacts with varied secondary amines, azoles and thiols to give 5-substituted-uracils efficiently. 5Diazouracil (1) is a significant bactericidela and carcinostatlb. As yet, however, reactions of 1 with nucleophiles am not been well defmed. k-f Water a