Reaction of 4,5-diamino-1,6-dihydropyrimidin-6-ones with two equivalents of chalcones
✍ Scribed by Braulio Insuasty; Monica Ramos; Rodolfo Moreno; Jairo Quiroga; Adolfo Sánchez; Manuel Nogueras; Norbert Hanold; Herbert Meier
- Book ID
- 112131316
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1995
- Tongue
- English
- Weight
- 331 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The reaction of 5,6-diamino-l,3-dimethyluracil with 1,3-diaryl-2,3-dibromopropan-l-ones gave {3-(5-amino-6imino-l,3-dimethyluracil)chalcones, and conditions for their cyclocondensation to pyrimidinodiazepines were found. For substantiation of the reaction mechanism, the reaction of the diamine with
## Abstract The reaction of the tetraaminopyrimidine 1 with the chalcones **2a‐f** yields, in the presence of catalytic amounts of acetic acid, the 1__H__‐pyrimido[4,5‐__b__][1,4]diazepine derivatives **3a‐f.** The cyclization process consists of a condensation reaction and a Michael type addition.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.