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ChemInform Abstract: Reaction of 4,5-Diamino-1,6-dihydropyrimidin-6-ones with Two Equivalents of Chalcones.

✍ Scribed by B. INSUASTY; M. RAMOS; R. MORENO; J. QUIROGA; A. SANCHEZ; M. NOGUERAS; N. HANOLD; H. MEIER

Book ID
112024184
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
26
Category
Article
ISSN
0931-7597

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The reaction of 5,6-diamino-l,3-dimethyluracil with 1,3-diaryl-2,3-dibromopropan-l-ones gave {3-(5-amino-6imino-l,3-dimethyluracil)chalcones, and conditions for their cyclocondensation to pyrimidinodiazepines were found. For substantiation of the reaction mechanism, the reaction of the diamine with