✦ LIBER ✦

Reaction of 3-bromobenzyl and 3-bromoacetyl coumarin with phosphites. Synthesis of some new phosphonates and phosphates in the coumarin series

✍ Scribed by Rositca Nikolova; Anka Bojilova; Nestor A. Rodios

Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 791 KB
Volume: 54
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(98)00892-8

No coin nor oath required. For personal study only.

✦ Synopsis

The reaction of 3-(l-bromobenzyl)coumarin 3 with trialkyl phosphites afforded in good yields the corresponding dialkyl phosphonates 5, the Arbuzov reaction products. The interaction of trialkyl phosphites with 3-(co-bromoacetyl)coumarin 4 gave the corresponding dialkyl vinylphosphates 8 as the only isolated products, whereas dialkyl phosphites reacted with 4 under phase transfer catalysis and gave vinylphosphates 8 or dialkyl 1,2-epoxy-ethylphosphonates 9. The ~oxo-phosphonates 7 were obtained from the reaction of hydrazono-derivative 10 with trialkyl phosphitos and the subsequent hydrolysis of the dialkyl ]~-hydrazono-phosphonates 11 thus formed.

📜 SIMILAR VOLUMES

ChemInform Abstract: Reaction of 3-Bromo

ChemInform Abstract: Reaction of 3-Bromobenzyl and 3-Bromoacetyl Coumarin with Phosphites. Synthesis of Some New Phosphonates and Phosphates in the Coumarin Series.

✍ Rositca Nikolova; Anka Bojilova; Nestor A. Rodios 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

A new conjugated addition of trialkyl ph

A new conjugated addition of trialkyl phosphites and alkylidenephosphoranes to 3-ω-azideoacetyl coumarin synthesis of some 1,2,3,4-triazaphospholes, triazoles, and azido-coumarin derivatives

✍ Ashraf A. Sediek; Abeer A. Shaddy; Wafaa M. Abdou 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 313 KB

## Abstract A new and efficient conjugate addition of trimethyl and triethyl phosphites to 3‐ω‐azidoacetylcoumarin **(****1****)** has been studied. The reaction proceeded smoothly at r.t. furnishing 1,2,3,4‐triazaphosphole coumarin derivatives **4a**, **4b** in ∼75% yields. Linear substituted tria

ChemInform Abstract: 3-(2,2-Dicyano-1-me

ChemInform Abstract: 3-(2,2-Dicyano-1-methylvinyl)coumarin in Heterocyclic Synthesis: Synthesis of Some New Coumarin Derivatives.

✍ M. R. SELIM 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

The reaction of 2-amino-3-cyano-4,5,6,7-

The reaction of 2-amino-3-cyano-4,5,6,7-tetrahydrobenzo[b]-thiophene with diethyl malonate: synthesis of coumarin, pyridine, and thiazole derivatives

✍ Rafat M. Mohareb; Fatma A. El-Omran; Jonathan Z. Ho 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 114 KB

## Abstract The reaction of 2‐amino‐3‐cyano‐4,5,6,7‐tetrahydrobenzo[b]thiophene (**1**) with diethyl malonate (**2**) gave two products: **3** and **4**. The reactivity of **3** toward a variety of chemical reagents was studied to give azoles, azines, and their fused derivatives. © 2001 John Wiley

Reaction of some substituted 2-allylphen

Reaction of some substituted 2-allylphenols with 2,3-dichloro-5, 6-dicyano-1,4-benzoquinone (DDQ) - a new method for the synthesis of coumarins

✍ K.V. Subba Raju; G. Srimannarayana; N.V. Subba Rao 📂 Article 📅 1977 🏛 Elsevier Science 🌐 French ⚖ 234 KB

Several methods are available for the synthesis of coumarin ring systeml. We nQy report a new method for the synthesis of coumarins by oxidative cyclisation of some substituted 2allylphenols by 2,3=dichloro-5,6-dicyano-1,4-bensoguinone 0). 7-Allyloxy-3-methylflavone2 on Claisen rearrangement b vacu

ChemInform Abstract: The Reaction of 2-A

ChemInform Abstract: The Reaction of 2-Amino-3-cyano-4,5,6,7-tetrahydrobenzo[b]-thiophene with Diethyl Malonate: Synthesis of Coumarin, Pyridine, and Thiazole Derivatives.

✍ Rafat M. Mohareb; Fatma A. El-Omran; Jonathan Z. Ho 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views