Reaction of 1,2,3,4-Tetrahydropyrimido[1,2-a]indol-10-ylmethyleniminium salts with certain nucleophilic agent
✍ Scribed by G. A. Golubeva; L. A. Sviridova; E. A. Makeeva; D. S. Komarov; B. I. Gorim
- Publisher
- Springer US
- Year
- 1995
- Tongue
- English
- Weight
- 565 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0009-3122
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## Abstract 3‐Benzylindole‐2‐carbohydrazides (4) on reaction with triethylorthoformate in a polar solvent like DMF yielded only 10‐benzyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino[4,5‐__a__]indoles (5) while (4) on reaction with triethylorthoacetate in DMF yielded both 10‐benzyl‐4‐methyl‐1,2‐dihydro‐1‐oxo‐1
## Abstract To find out whether the 1,4‐addition to 1,2:3,4‐diepoxides, which so far has been observed only once, is of a more general character, we investigated the reaction of a variety of O‐, C‐, N‐, and S‐nucleophiles with the model compound 1,2:3,4‐diepoxy‐2,3‐dimethylbutane (__Scheme 4__). In