Reaction of 1-chloromethyl-4,5-dichloropyridazin-6-one
✍ Scribed by Hyun-A Chung; Young-Jin Kang; Yong-Jin Yoon
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1998
- Tongue
- English
- Weight
- 283 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
Reaction of 1‐chloromethyl‐4,5‐dichloropyridazin‐6‐one with some nucleophiles such as sodium methoxide, sodium azide, 2‐mercaptopyrimidine and phenol gave 2, 3, 4, 7, 8 and 10. 5‐Chloro‐4‐phenoxypyridazin‐6‐one (10) was also synthesized from 8 through 9.
📜 SIMILAR VOLUMES
## Abstract Direct functionalization of 4,5‐dichloropyridazin‐6‐one with some nucleophiles in seven solvents gave regioselectively 5‐halo‐4‐substituted‐pyridazin‐6‐ones as main product. Reaction of 4,5‐dichloropyridazin‐6‐one with 2‐mercaptopyrimidine (2 equivalents) also afforded 4,5‐di(pyrimidin‐
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v