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Direct functionalization of 4,5-dichloropyridazin-6-one

✍ Scribed by Hyun-A Chung; Deok-Heon Kweon; Young-Jin Kang; Jung-Won Park; Yong-Jin Yoon


Publisher
Journal of Heterocyclic Chemistry
Year
1999
Tongue
English
Weight
451 KB
Volume
36
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

Direct functionalization of 4,5‐dichloropyridazin‐6‐one with some nucleophiles in seven solvents gave regioselectively 5‐halo‐4‐substituted‐pyridazin‐6‐ones as main product. Reaction of 4,5‐dichloropyridazin‐6‐one with 2‐mercaptopyrimidine (2 equivalents) also afforded 4,5‐di(pyrimidin‐2‐ylsulfanyl)pyridazin‐6‐one as the main product.


📜 SIMILAR VOLUMES


Reaction of 1-chloromethyl-4,5-dichlorop
✍ Hyun-A Chung; Young-Jin Kang; Yong-Jin Yoon 📂 Article 📅 1998 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 283 KB

## Abstract Reaction of 1‐chloromethyl‐4,5‐dichloropyridazin‐6‐one with some nucleophiles such as sodium methoxide, sodium azide, 2‐mercaptopyrimidine and phenol gave 2, 3, 4, 7, 8 and 10. 5‐Chloro‐4‐phenoxypyridazin‐6‐one (10) was also synthesized from 8 through 9.

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v