Reactant- and product-based approaches to the design of combinatorial libraries
โ Scribed by Valerie J. Gillet
- Book ID
- 110407251
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 176 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1381-1991
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
It is not enough to select a chemistry, build a combinatorial library, and test it for biologically active compounds. Chemical libraries can serve different purposes and it is reasonable that they should be designed in light of their purpose and the information available on structural properties imp
The design of combinatorial libraries involves the consideration of all synthesizable compounds (the virtual library), followed by the selection of a suitably sized subset for actual synthesis and experimentation. Several approaches to this task can be envisaged, involving either reagent-based or pr