System issues: Evaluation of the in vivo
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W. Suter; R. Ahiabor; B. Blanco; F. Locher; F. Mantovani; M. Robinson; G. Sreena
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Article
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1996
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John Wiley and Sons
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English
Three genotoxic mouse carcinogens, 4 c h l o r wphenylenediamine (4-C-o-PDA), 2-nitro-p-phenylenediamine (2-N-pPDA), and 2,4diaminotoluene (2,4-DAT), were tested in the Big BlueTM transgenic mouse mutation assay. Each experiment consisted of a vehicle control group with ten Big BlueTM C57BL/6 mice,