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Evaluation of di-(2-ethylhexyl)phthalate and its major metabolites in the ames test and L5178Y mouse lymphoma mutagenicity assay

โœ Scribed by Kirby, P. E. ;Pizzarello, R. F. ;Lawlor, T. E. ;Haworth, S. R. ;Hodgson, J. R.


Publisher
Wiley (John Wiley & Sons)
Year
1983
Weight
369 KB
Volume
5
Category
Article
ISSN
0192-2521

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โœ Putman, D. L. ;Moore, W. A. ;Schechtman, L. M. ;Hodgson, J. R. ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Wiley (John Wiley & Sons) โš– 283 KB ๐Ÿ‘ 1 views

Di-(2-ethylhexyl)phthalate (DEHP) and its two major metabolites, mono-(2-ethyl-hexy1)phthalate (MEHP) and 2-ethylhexanol (EH), were evaluated for their ability to induce chromosomal damage in male Fischer 344 rats after oral administration. Dose levels, the highest of which represents one-tenth of t