Re-emergence of anti-topoisomerase I antibody with exacerbated development of skin sclerosis in a patient with systemic sclerosis
✍ Scribed by Yasuhito Hamaguchi; Manabu Fujimoto; Minoru Hasegawa; Takashi Matsushita; Kazuhiko Takehara
- Book ID
- 116585505
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 183 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1097-6787
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## Abstract ## Objective To describe the clinical and laboratory features and natural history of the disease in systemic sclerosis (SSc; scleroderma) patients with anti–topoisomerase I (anti–topo I) antibody who have different skin thickness progression rates (STPRs). ## Methods SSc patients (n
## Abstract ## Objective To determine any associations of the __PTPN22__ R620W single‐nucleotide polymorphism (SNP) with systemic sclerosis (SSc) or with anticentromere antibody (ACA)–positive or anti–topoisomerase I (anti–topo I) antibody–positive SSc, in a case–control study of US white, black,