The switch from pRb/p105 to Rb2/p130 in
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Heike Helmbold; Umberto Galderisi; Wolfgang Bohn
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Article
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2011
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John Wiley and Sons
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English
⚖ 182 KB
## Abstract Cellular senescence is a response to genotoxic stress that results in an irreversible cell cycle arrest. Activation of this pathway relies on the activity of the retinoblastoma proteins and proteins of the DNA damage response cascade. Here, we discuss the functional relevance of the swi